StatisticsÜyeler: 302
Haberler: 287
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Ziyaretçiler: 452211
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Yazan Administrator
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In Silico P275 Biosimulation of acetaminophen-induced liver injury
Harvey J. Clewell, The Hamner Institute for Health Sciences; Brett Howell, The Hamner Institute for Health Sciences; Yuching Yang, The Hamner Institute for Health Sciences; Alison Harrel, The Hamner Institute for Health Sciences; Scott Siler, Entelos, Inc.; Richard Ho, Entelos, Inc.; Rukmini Kumar, Entelos, Inc.; Melvin Andersen, The Hamner Institute for Health Sciences; Paul Watson, The Hamner Institute for Health Sciences P284 Prediction of regioselectivity and order of the occurrence for CYP-mediated reaction
Yasushi Yamazoe, Tohoku University, Graduate School of Pharmaceutical Sciences; Kazumi Ito, Tohoku University, Graduate School of Pharmaceutical Sciences; Kouichi Yoshinari, Tohoku University, Graduate School of Pharmaceutical Sciences P274 Automatically Finding Drug Discovery 'Rules of Thumb'
Edmund J. Champness, Optibrium Ltd.; Matthew D. Segall, Optibrium Ltd.; Tatsunori Hashimoto, Harvard University P278 Evaluation Of ACD/ADME Suite 5.0 Regioselectivity Predictions
Justas Dapkunas, ACD/Labs, Inc.; Remigijus Didziapetris, ACD/Labs, Inc.; Andrius Sazonovas, ACD/Labs, Inc.; Pranas Japertas, ACD/Labs, Inc. P280 In Silico Prediction of Biotransformation Pathways: Decarboxylation of Aliphatic and Aromatic Compounds
Ernest Murray, Lhasa Limited; Mohammed A. Ali, Lhasa Limited; Anthony Long, Lhasa Limited P277 Comparison of In Silico Tools for the Prediction of Sites of Metabolism by Cytochrome P450
Hoa Le, Genentech; Young Shin, Genentech; Cornelis Hop, Genentech; Cyrus Khojasteh, Genentech P279 Guiding Focused Design of Potent Leads with Improved Metabolic Stability
Matthew D. Segall, Optibrium Ltd. P282 Pattern-recognition-based Prediction of Metabolic Regioselectivity Mediated by Human Cytochromes P450 3A4
Chunzhi Ai, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Yuxi Mao, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P276 Classification models for CYP450 2C8 inhibitors and non-inhibitors
Pei-Pei Dong, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Chunzhi Ai, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Yan-Yan Zhang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P283 Prediction of Drug-Drug Interactions of Two New Antibiotics Using a Mechanistic Static Model
Arnaud M. Bruyere, Xénoblis; Cristina Lopez, Aureus Pharma; Olivier Barberan, Aureus Pharma; Françoise Brée, Xénoblis P281 Modeling Toxicity Endpoints Using Artificial Neural Network Ensembles
Adam C. Lee, Simulations Plus, Inc.; Robert Fraczkiewicz, Simulations Plus, Inc.; W.S. Woltosz, Simulations Plus, Inc. |
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Yazan Administrator
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Metabolic profiling P320 Definitive Assignment of Metabolite Structures Using Ion Mobility Mass Spectrometry And Molecular Modeling
John P. Shockcor, Waters Corp; Iain D. Campuzano, Waters Corp; Jayne Kirk, Waters Corp; Gordon Dear, GlaxoSmithKline; Jordi Munoz-Muriedas, GlaxoSmithKline P324 Identification and Screening Major Metabolites of K2-spices in Human Liver Microsome and Human Urine
Hua-fen Liu, AB Sciex; Sumandeep Rana, Redwood Toxicology; Alex Wang, AB Sciex; Andre Schreiber, AB Sciex; Elliott Jones, AB Sciex P329 The Simultaneous Collection of MRM and MS/MS Data To Detect and Quantify Drug Metabolites
Joanne Mather, Waters Corporation; Marian Twohig, Waters Corporation; Rob Plumb, Waters Corporation P323 Evaluation of Active Counting Mode option in LabLogic beta;-RAM Model 5 and Laura software
Huw W. Loaring, LabLogic Systems Ltd.; Andrew Williams, LabLogic Systems Ltd.; Jonathan Trevor Attwood, AstraZeneca R & D-Charnwood; Brett O'Brien, AstraZeneca R & D-Charnwood P326 Metabolite Detection and Identification Using Fragment Ion Search in Conjunction with Automated Fragment Prediction
Robert Mistrik, HighChem, Ltd.; Juraj Lutisan, HighChem, Ltd.; Milos Suchy, HighChem, Ltd.; Alexej Nikiforov, Univeristy of Vienna; Yingying Huang, Thermo Fisher Scientific P327 Rapid Metabolite Profiling of in vivo Metabolites of Escultin in Rat Using Ultra-Fast Liquid Chromatography Combined with Tandem Mass Spectrometry
Guangbo Ge, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Si-Cheng Liang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Zhong-Ze Fang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P321 Detection and Identification of the Metabolites of Daphnetin in Rat Plasma by LC-ESI Tandem Mass Spectrometry
Si-Cheng Liang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Guang-Bo Ge, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Zhong-Ze Fang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Peipei Dong, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P322 Enhanced Metabolite Identification and Structural Elucidation With a Semi-Automated Software
B. Bonn, University of Gothenburg; Carina Leandersson, AstraZeneca R&D Molndal; Fabien Fontaine, Lead Molecular Design, S.L.; Ismael Zamora, Lead Molecular Design, S.L. P319 Biotransformation Studies of 4-Amino-N-cyclopropyl-8-(3,6-dimethoxypyridazin-4-yl)-7-fluorocinnoline-3-carboxamide, An Orally Active Sub-type Selective GABA-Aá2/3 Receptor Positive Modulator and the Approaches to Remove Its Bioactivation Liabilities
Jian Yu, AstraZeneca Pharmaceuticals LLP; Maria D. Ribadeneira, AstraZeneca Pharmaceuticals LLP P325 In Vivo Metabolite Identification and Profiling Using a Rapid, Accurate Mass, High Resolution Mass Spectrometer: Quantitative and Qualitative Results from One Injection
James A. Ferguson, AB SCIEX; Jeffrey D. Miller, AB SCIEX; Sandeepraj Pusalkar, Millennium Pharmaceuteicals, Inc. P328 Simultaneous High Throughput Enzyme Stability Quantitation and Drug Soft Spot Metabolite Analysis using a new style TOF LCMS
Elliott Jones, AB Sciex |
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Yazan Administrator
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High throughput techniques P269 HTS for selective muscarinic cholinergic receptors antagonists
Valerii D. Tonkopii, Institute of Limnology Rus.Acad.Sci. P270 In-vitro Distribution Dialysis Technique for Multiple Tissue Protein Binding
Mark G. Qian, Millennium Pharmaceuticals, Inc.; Cindy Xia, Millennium Pharmaceuticals, Inc.; Susan Chen, Millennium Pharmaceuticals, Inc.; Frank Lee, Millennium Pharmaceuticals, Inc.; Tai-Nang Huang, Linden Bioscience P271 Software algorithms for high resolution LC-MS analysis in early drug discovery: quantitative and qualitative screening in the same run
Karen Salomon, ThermoFisher Scientific; Xiaojie Ding, ThermoFisher Scientific; Jim Shofstahl, ThermoFisher Scientific; Thomas McClure, ThermoFisher Scientific; Rose Herbold, ThermoFisher Scientific; Hans Pfaff, ThermoFisher Scientific P273 The End of MRM: Ultrafast SPE-TOF Analysis Streamlines Workflow and Increases Throughput of ADME Assays
Michelle V. Romm, BIOCIUS Life Sciences; Nikunj Parikh, BIOCIUS Life Sciences; Vaughn P. Miller, BIOCIUS Life Sciences; William A. LaMarr, BIOCIUS Life Sciences; Can C. Ozbal, BIOCIUS Life Sciences P267 A New HTS Approach to Study the Interactions of Multiple Compounds with Individual Human UDP-glucuronosyltransferase; UGT1A6 as a Model
Anne M. Soikkeli, University of Helsinki; Mika Kurkela, University of Helsinki; Marjo Yliperttula, University of Helsinki; Jouni Hirvonen, University of Helsinki; Moshe Finel, University of Helsinki P272 Study of the effect of granulation technique on physicochemical properties of piroxicam liquisolid compacts
MH Zarrintan, Tabriz University of Medical Sciences; Y. Javadzadeh, Tabriz University of Medical Sciences; K. Salarmand, Tabriz University of Medical Sciences P268 A Universal Spectroscopic Technique for High-Throughput In Situ Measurement of Cytochrome P450 Catalysis
Matthew J. Traylor, University of California, Berkeley; Eric S. Arnon, University of California, Berkeley; Jonathan S. Dordick, Rensselaer Polytechnic Institute; Douglas S. Clark, University of California, Berkeley |
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Yazan Administrator
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Pharmacokinetics and Pharmacodynamics P421 Interspecies allometric scaling of therapeutic monoclonal antibodies
Masataka Oitate, Daiichi Sankyo Co., Ltd.; Noriko Masubuchi, Daiichi Sankyo Co., Ltd.; Takashi Ito, Daiichi Sankyo Co., Ltd.; Yoshiyuki Yabe, Daiichi Sankyo Co., Ltd.; Tsuyoshi Karibe, Daiichi Sankyo Co., Ltd.; Takanori Aoki, Daiichi Sankyo Co., Ltd.; Nobuyuki Murayama, Daiichi Sankyo Co., Ltd.; Atsushi Kurihara, Daiichi Sankyo Co., Ltd.; Noriko Okudaira, Daiichi Sankyo Co., Ltd. P422 Comparison of pharmacokinetics of dapsone in rats following blood sampling via retro-orbital, jugular vein and saphenous vein
Tausif Ahmed, Sai Advantium Pharma Ltd; Prashant N, Sai Advantium Pharma Ltd; Sudipta B, Sai Advantium Pharma Ltd; Rajanikanta S, Sai Advantium Pharma Ltd; Vijay J, Sai Advantium Pharma Ltd; Abdul B, Sai Advantium Pharma Ltd; Kaustubh T, Sai Advantium Pharma Ltd; Amol G, Sai Advantium Pharma Ltd; Sireesha D, Sai Advantium Pharma Ltd; Swapnakumari T, Sai Advantium Pharma Ltd; Subrahmanyam V, Sai Advantium Pharma Ltd P423 Development of the Next Generation of On-Line Radiochromatography Detectors
Tom Deakin, The University of Sheffield; Lee F. Thompson, The University of Sheffield; John K. Clapham, LabLogic Systems Ltd.; Richard A. Brown, LabLogic Systems Ltd. P424 Anti-Arthritis Effect of a Novel Bruton's Tyrosine Kinase Inhibitor in Rat Collagen-Induced Arthritis and Mechanism-Based Pharmacokinetic/Pharmacodynamic Modeling: Relationships between Inhibition of BTK Phosphorylation and Efficacy
Lichuan Liu, Genentech; Julie Di Paolo, CGI Pharmaceuticals; Jim Barbosa, CGI Pharmaceuticals; Hong Rong, CGI Pharmaceuticals; Karin Reif, Genentech; Harvey Wong, Genentech, Inc P425 PK-PD Modeling of Combination Efficacy Effect from Administration of a MEK Inhibitor, GDC-0973 and PI3K Inhibitor, GDC-0941 in A2058 Xenografts
Edna F. Choo, Genentech Inc; Marcia Belvin, Genentech Inc; Klaus Hoeflich, Genentech Inc; Mark Merchant, Genentech Inc; Douglas Dan Otter, Genentech Inc; Laurent Salphati, Genentech Inc P426 Pharmacokinetics of Subcutaneous Single Doses of Pegylated Recombinant Human Growth Hormone(PEG-rhGH)in rhesus Monkeys
Yong M. Cai, Tianjin University,Tianiin Institute of Pharmaceutical Research; M. Li, Tianiin Institute of Pharmaceutical Research; Zong P. Zhang, Tianiin Institute of Pharmaceutical Research; Zheng M. Chen, Tianiin Institute of Pharmaceutical Research; Chang X. Liu, Tianiin Institute of Pharmaceutical Research P427 Preclinical Profiling, Prediction of Human Pharmacokinetics and Pharmacokinetic-Pharmacodynamic Modeling of a Potent and Selective Met Kinase Inhibitor
Bianca M. Liederer, Genentech, Inc.; Leonid M. Berezhkovskiy, Genentech, Inc.; Brian Dean, Genentech, Inc.; Vikki Dinkel, Array BioPharma, Inc.; John Gaudino, Array BioPharma, Inc.; Mark Merchant, Genentech, Inc.; Emile Plise, Genentech, Inc.; Dan Sutherlin, Genentech, Inc.; Harvey Wong, Genentech, Inc.; Xingrong Liu, Genentech, Inc. P428 Pharmacokinetics, Disposition and Metabolism of A Novel Peptidomimetic in the Rat
Bin Ma, The Chinese University of Hong Kong; Chun Yin, The Chinese University of Hong Kong; Dan Yang, The University of Hong Kong; Ge Lin, The Chinese University of Hong Kong P429 Changes in Expression and Function of Pept1 in Indomethacin-induced Acute Intestine Injury in Rats and Damaged Caco-2 Cells after Treatment of JBP485
Kexin Liu, Dalian Medical University; Wei Wang, Dalian Medical University; Qi Liu, Dalian Medical University; Changyuan Wang, Dalian Medical University; Qiang Meng, Dalian Medical University; Jian Zhang, Dalian Medical University; Xinjin Guo, Dalian Medical University; Taiichi Kaku, Bioproducts Industry Co. Ltd. P430 Pharmacokinetic interactions between three major bioactive flavones in Radix Scutellariae
Chenrui Li, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong; Ge Lin, The Chinese University of Hong Kong; Zhong Zuo, The Chinese University of Hong Kong P431 Blood Sampling Method Influences Pharmacokinetics in the Rat
Natasha Nikolaidis, BASi; Candace Rohde-Johnson, BASi; Nick Suttles, BASi; R. Tyler DeGraw, BASi; Nathanael Lichti, Purdue University; Rachel Sun, BASi; David Hopper, BASi P432 Pharmacokinetics and NONMEM analysis of curcumin and its metabolite THC
Habibur SM Rahman, PSG College of Pharmacy; Ramanathan M, PSG College of Pharmacy P433 Pharmacokinetics (PK) and pharmacodynamics (PD) of RO4929097 (RO), a novel gamma secretase inhibitor, in a phase I study in patients with advanced solid tumors
Karen Wang, Hoffman-La Roche P434 Pharmacokinetics of recombinant human apolipoprotein(a) kringle V in rats
Byoung Soo Kim, Korea Institute of Radiological and Medical Science; Eun Jung Kim, Korea Institute of Radiological and Medical Science; Jang Seong Kim, Mogam Biotechnology Research Institute; Gi Jeong Cheon, Korea Institute of Radiological and Medical Science; Ho Jeong Lee, Mogam Biotechnology Research Institute; Tae Hyun Choi, Korea Institute of Radiological and Medical Science P435 Accurate prediction of variability in CLint and Fm via 3A4 is only obtained by assessing a series of individual cryopreserved human hepatocyte batches
Coraline Desbans, KaLy-Cell; Constanze Hilgendorf, AstraZeneca R&D; Lysiane Richert, KaLy-Cell; Mareike Lutz, AstraZeneca R&D; Anna-Lena Ungell, AstraZeneca R&D P436 Single rat full PK-profiling to allow for better science and for the use of less testing animals
Mira Wenker, NOTOX B.V.; Michael Eman, NOTOX B.V.; Danielle Broekhuizen, NOTOX B.V.; Theo Noij, NOTOX B.V.; Harry Emmen, NOTOX B.V. P437 Pre-clinical pharmacokinetic studies of hemoglobin-vesicle as an artificial oxygen carrier
Kazuaki Taguchi, Kumamoto University; Toru Maruyama, Kumamoto University; Hiroshi Watanabe, Kumamoto University; Hiromi Sakai, Waseda University; Eishun Tsuchida, Waseda University; Masaki Otagiri, Kumamoto University P438 Absorption, Distribution, Metabolism and Excretion (ADME) Study With a Potent Thiazolidinedione Insulin Sensitizer, Lobeglitazone
Se-Mi Kim, Chong Kun Dang Pharm; Nina Ha, Chong Kun Dang Pharm; Kyu-Tae Park, Chong Kun Dang Pharm; Hyun-Tak Oh, Chong Kun Dang Pharm; Hosung Yu, Chong Kun Dang Pharm; Young Min Kim, Chong Kun Dang Pharm; Sungsook Lee, Chong Kun Dang Pharm; Dal-Hyun Kim, Chong Kun Dang Pharm P439 Pharmacokinetics of tiapride and its principal metabolite in human blood plasma
Milan Nobilis, Institute of Experimental Biopharmaceutics , Joint Research Centre of AV CR and PRO.MED.CS; Zuzana Vybíralová, Institute of Experimental Biopharmaceutics , Joint Research Centre of AV CR and PRO.MED.CS; Barbora Szotáková, Faculty of Pharmacy, Charles University; Kveta Sládková, Institute of Experimental Biopharmaceutics , Joint Research Centre of AV CR and PRO.MED.CS; Martin Kunes, Institute of Experimental Biopharmaceutics , Joint Research Centre of AV CR and PRO.MED.CS; Zbynek Svoboda, Institute of Experimental Biopharmaceutics , Joint Research Centre of AV CR and PRO.MED.CS P440 Absorption, Distribution, Metabolism and Excretion (ADME) Study of a Potent Thiazolidinedione Insulin Sensitizer, Lobeglitazone P441 Pharmacokinetics of recombinant human basic fibroblast growth factor following intravenous bolus plus infusion in rhesus monkey
Xiuwen Liu, Beijing Institute of Radiation Medicine; Zhongming Tang, Beijing Institute of Radiation Medicine; Haifeng Song, Beijing Institute of Radiation Medicine; Baozhen Zhu, Beijing Institute of Radiation Medicine |
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Yazan Administrator
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Pharmacogenetics/Pharmacoepigenetics P411 Frequencies of three CYP2D6 nonfunctional alleles (CYP2D6*3, *4, and *6), and the metabolic capacity of CYP2D6 in Northern Iranian Population (Mazandaran)
Mohammad R. Shiran, Faculty of Medicine, Mazandaran University of Medical Sciences; Mohammad B. Hashemi Soteh, Faculty of Medicine, Mazandaran University of Medical Sciences; Fatemeh Merat, Faculty of Medicine, Mazandaran University of Medical Sciences; Fatemeh Sarzare, Faculty of Medicine, Mazandaran University of Medical Sciences; Ebrahim Salehifar, Faculty of Medicine, Mazandaran University of Medical Sciences P413 HLA-B*1502 Allele in Chinese mainland patients with carbamazepine induced Stevens-Johnson syndrome and toxic epidermal necrolysis
Yan Zhang, The First Affiliated Hospital of Soochow University; Wei Peng, The First Affiliated Hospital of Soochow University; L.Y. Miao, The First Affiliated Hospital of Soochow University P406 CYP2D6 Genotype and Phenotype Determination in the Hausa, Ibo and Yoruba Ethnic Populations of Nigeria
Benjamin U. Ebeshi, Niger Delta University; Oluseye O. Bolaji, Obafemi Awolowo University; Alice Matimba, University of Cape Town; Collen M. Masimirembwa, African Institute of Biomedical Science & Technology P398 Allopurinol –induced severe cutaneous adverse drug reactions in a Thai population is strongly associated with HLA-B*5801
Wongwiwat Tassaneeyakul, Faculty of Pharmaceutical Sciences, Khon Kaen University; Somsak Tiamkao, Faculty of Medicine, Khon Kaen University; Napat Prabmeechai, Khon Kaen University; Thawinee Jantararoungtong, Faculty of Medicine, Khon Kaen University; Pei Chen, Academia Sinica; Pao-Yu Lin, Academia Sinica; Pansu Chumworathayi, Khon Kaen University; Usanee Khunarkornsiri, Udornthani Hospital; Parinya Konyoung, Udornthani Hospital; Pachadaporn Chucherd, Surin Hospital; Suda Vannaprasaht, Khon Kaen University; Charoen Choonhakarn, Khon Kaen University; Alisara Sangviroon, Police General Hospital; Wichittra Tassaneeyakul, Khon Kaen University P401 Association of HLA-B*1502 and severe cutaneous adverse reactions caused by aromatic antiepileptic drugs
Wichittra Tassaneeyakul, Khon Kaen University; Somsak Tiamkao, Faculty of Medicine, Khon Kaen University; Napat Prabmeechai, Khon Kaen University; Thawinee Jantararoungtong, Faculty of Medicine, Khon Kaen University; Pei Chen, Academia Sinica; Shu-Yi Lin, Academia Sinica; Wei-Hsuan Chen, Academia Sinica; Pansu Chumworathayi, Khon Kaen University; Usanee Khunarkornsiri, Udornthani Hospital; Parinya Konyoung, Udornthani Hospital; Alisara Sangviroon, Police General Hospital; Patcharee Kanjanawat, Sappasitthiprasong Hospital; Arkhom Arayawhichanont, Sappasitthiprasong Hospital; Charoen Choonhakarn, Khon Kaen University; Kongkiat Kulkantrakorn, Thammasart University P420 The effect of related metabolizing enzyme polymorphism and active metabolites on thiopurine treatment in inflammatory bowel disease
Min Huang*, Sun Yat-sen University; Liang Ding, Sun Yat-sen University; Pin-jin Hu, Sun Yat-sen University; Xue-ding Wang, Sun Yat-sen University; Hui-chang Bi, Sun Yat-sen University P410 EPHX1 GENE TYR113HIS VARIANT ALONE, or in COMBINATION with XRCC1 ARG399GLN POLYMORPHISM SIGNIFICANTLY and CONSIDERABLY INCREASED THE RISK of CHILDHOOD ACUTE LYMPHOBLASTIC LUKEMIA
Tugba Boyunegmez Tumer, Çanakkale Onsekiz Mart University; Duygu Yilmaz, Middle East Technical University; Cihan Tanrikut, Middle East Technical University; Gulen Ulusoy, Middle East Technical University; Emel Arinç, Middle East Technical University P408 Effect of sildenafil citrate (Viagra®) on trace element concentration in serum and brain of rats
Abdel-Hasseb A. Fayed, Faculty of Veterinary Medicine P407 Development of Real-Time PCR VKORC1 and CYP2C9 Genotyping Method for Dose Adjustment of Anticoagulant Warfarin
Woochang Lee, Asan Medical Center; Hee-Jung Chung, Asan Medical Center; Sollip Kim, Asan Medical Center; Eun Ju Cho, Asan Medical Center; Hye Won Lee, Asan Medical Center; Hae-Joon Park, Bioneer Corporation; Sail Chun, Asan Medical Center; Won-Ki Min, Asan Medical Center P419 The Alteration of the Genetic Variants of CYP2A13 on Courmarin 7-hydroxylation and Frequency Distribution of the Genetic Variants of CYP2A13 in a Chinese Han Population
Ting Liu, College of Pharmaceutical Sciences Zhejiang University; Jun-Yan Hong, School of Public Health/EOHSI, University of Medicine and Dentistry of New Jersey; Su Zeng, College of Pharmaceutical Sciences, Zhejiang University; Shuqing Chen, College of Pharmaceutical Sciences Zhejiang University P409 Effects of Polymorphic ABCG2 and SLC2A9 on the serum Uric Acid Levels in Korean Healthy Subjects
Kyoung-Ah Kim, Anam Hospital, Korea University College of Medicine; Hyun-Jin Joo, Anam Hospital, Korea University College of Medicine; Ji-Young Park, Anam Hospital, Korea University College of Medicine P403 Association of XPD Asp312Asn polymorphism with cisplatin-related toxicities and treatment outcome in malignant mesothelioma
Nina Erculj, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana; Vita Dolzan, Institute of Biochemistry, Faculty of Medicine, University of Ljubljana; Viljem Kovac, Institute of Oncology, University of Ljubljana P412 Genetic Polymorphism of Metabolizing Enzymes: Influence on DNA Damage, Paraoxonase and AChE Activity in Pesticide Exposed Subjects
Satyender Singh, National Centre for Disease Control; Vivek Kumar, UCMS & GTB Hospital; Grover S S, National Centre for Disease Control; Rawat D S, National Centre for Disease Control; Pasha S T, National Centre for Disease Control; Jain S K, National Centre for Disease Control; B. D. Banerjee, UCMS & GTB Hospital P402 Association of serotonin transporter gene (SLC6A4) polymorphisms with alcohol dependence in a Turkish population
Ozgur R. Karaca, Hacettepe University, Faculty of Medicine; Melih O. Babaoglu, Hacettepe University, Faculty of Medicine; Umit Yasar, Hacettepe University, Faculty of Medicine; Yavuz Ayhan, Hacettepe University, Faculty of Medicine; Can S. Gurel, Hacettepe University, Faculty of Medicine; Nesrin Dilbaz, Ankara Numune Education and Research Hospital; Basaran Demir, Hacettepe University, Faculty of Medicine; Berna Ulug, Hacettepe University, Faculty of Medicine; Atilla Bozkurt, Hacettepe University, Faculty of Medicine P400 Association of Estrogen Receptor α Gene Polymorphism with Bone Mineral Density and Body Mass Index in Turkish Postmenopausal Women
Ozlem Kurt, Istanbul University; Hulya Yilmaz Aydogan, Istanbul University; Turgay Isbir, Yeditepe University; Mehmet Uyar, Uskudar State Hospital; Ayse Can, Istanbul University P416 Investigation of association between paraoxonase-1 192/55 polymorphisms and serum paraoxonase activity in lung cancer
Pinar Aksoy, İstanbul University; Bedia Agachan, Istanbul University; Turgay Isbir, Yeditepe University; Ahmet Kizir, Istanbul University; Erkan Topuz, Istanbul University; Hakan Berkkan, Istanbul Bilim University P404 Comparison of functional CYP2A6 polymorphisms among three Asian populations
Yin-Jin Jang, Pharmacogenomics Research Center; Woo-Young Kim, Pharmacogenomics Research Center; Jae-Gook Shin, Inje University College of Medicine and Busan Paik Hospital; Sang Seop Lee, Pharmacogenomics Research Center P397 Affymetrix DMET™Plus Genotyping Technology : Evaluation of Cell Lines and Healthy Volunteer Samples
Tracy Mills, AstraZeneca; Mark Pilling, AstraZeneca; Glynis Nicholls, AstraZeneca; Tommy B. Andersson, Clinical Pharmacology and DMPK; Petter Björquist, Cellartis AB; Anders Aspegren, Cellartis AB; Peter Sartiby, Cellartis AB P417 Pharmacogenomic factors of tamoxifen efficacy in women with early breast cancer
Ondrej Slanar, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital; Sona Argalácsová, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital; L. Petruželka, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital; B. Konopásek, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital; M. Drazdakova, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital; A. Cerna, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital; T. Zima, 1st Faculty of Medicine, Charles University in Prague and General Teaching Hospital P418 Protective Role of DNA Repair XRCC3 Thr241Met Polymorphism on Development of Childhood Acute Lymphoblastic Leukemia
Cihan Tanrikut, Middle East Technical University; Tugba Boyunegmez Tumer, Canakkale Onsekiz Mart University; Emel Arinç, Middle East Technical University P414 Implication of genetic polymorphisms in CYP2C9 and CYP2C19 on drug metabolism in isolated cryopreserved human hepatocytes
Roberto Tolando, Celsis In Vitro Technologies; Caitlin Brown, Celsis In Vitro Technologies; Scott Heyward, Celsis In Vitro Technologies P399 Alteration of DNA methylation as an early event for non-genotoxic carcinogens
Sibel Ozden, Faculty of Pharmacy, Istanbul University; Tao Chen, The University of Birmingham; Wolfgang Dekant, University of Wuerzburg; J. Kevin Chipman, The University of Birmingham; Angela Mally, University of Wuerzburg P405 Confounding Effects of C57BL/6 Substrains in Toxicology
Mohammed Bourdi, Laboratory of Molecular Immunology, National Heart,Lung and Blood Institute, National Institutes of Health, DHHS; John S. Davies, Laboratory of Molecular Immunology, National Heart,Lung and Blood Institute, National Institutes of Health, DHHS; Nalini Raghavachari, NHLBI; Delong N. Liu, NIH; Khalid Sendide, Laboratory of Molecular Immunology, National Heart,Lung and Blood Institute, National Institutes of Health, DHHS; Peter J. Munson, NIH; Lance R. Pohl, Laboratory of Molecular Immunology, National Heart,Lung and Blood Institute, National Institutes of Health, DHHS P415 In Vivo and In Vitro Pharmacokinetic Characterization of Calycosin
Jianqing Ruan, University of Macau; Yitao Wang, Institute of Chinese Medical Sciences, University of Macau; Ru Yan, University of Macau |
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