StatisticsÜyeler: 302
Haberler: 287
Bağlantılar: 0
Ziyaretçiler: 452217
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Yazan Administrator
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Non-P450 phase I enzymes P370 Adaptive Response to Reactive Aldehydes in Mouse Liver: Role of Aldehyde dehydrogenases
Russell A. Prough, U. Louisville School of Medicine; Ngome L. Makia, U. Louisville School of Medicine; Daniel J. Conklin, U. Louisville School of Medicine P371 Arylacetamide deacetylase is a determinant enzyme for the difference in hydrolase activities of phenacetin and acetaminophen
Tatsuki Fukami, Faculty of Pharmaceutical Sciences, Kanazawa University; Akinobu Watanabe, Faculty of Pharmaceutical Sciences, Kanazawa University; Shiori Takahashi, Faculty of Pharmaceutical Sciences, Kanazawa University; Yuki Kobayashi, Faculty of Pharmaceutical Sciences, Kanazawa University; Nao Nakagawa, Faculty of Pharmaceutical Sciences, Kanazawa University; Miki Nakajima, Faculty of Pharmaceutical Sciences, Kanazawa University; Tsuyoshi Yokoi, Faculty of Pharmaceutical Sciences, Kanazawa University P372 Baeyer-Villiger Oxidation Specifically Catalyzed By Human Flavin-Containing Monooxygenase 5 (FMO5)
W. George Lai, Eisai Inc.; Nadia F. Misiaszek, Eisai Inc.; George A. Moniz, Eisai Inc.; Y. Nancy Wong, Eisai Inc. |
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Yazan Administrator
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Mechanisms of xenobiotic toxicities P316 Testosterone influences the antioxidative enzymes activity in benzene treated rats
Yeshvandra Verma Sr., C.C.S.University, Meerut P301 Cyclopiazonic acid toxic effects on the liver and kidneys: biochemical and histopathological studies
Hassan Malekinejad, Urmia University; Peyman Akbari, Urmia University P298 Attenuation of Neurotoxicity Induced by Sub-Chronic Paraquat Administration in Rats by Deprenyl, Quercetin, Green Tea or Malt Extract
Nesrine Salah El Dine El Sayed, Lecturer of Pharmacology & Toxicology; Hala Fahmy Zaki, Associate professor of Pharmacology & Toxicology P308 Human Polymorphisms in the Glutathione Transferase Zeta 1 Maleylacetoacetate Isomerase Gene Predict the Kinetics and Toxicity of Dichloroacetate
Peter W. Stacpoole, University of Florida College of Medicine P297 Association of blood level of methemoglobin with clinical outcome of patients with aluminium phosphide poisoning
Babak Mostafazadeh, Shaheed Beheshty University Of Medical Sciences; Esmaeil Farzaneh, Ardabil University Of Medical Sciences; Tahmineh Afsharian, Private Physician P299 Benefit Effect of Naloxone in Benzodiazepines Intoxication:Findings of a Preliminary Study
Babak Mostafazadeh, Shaheed Beheshty University Of Medical Sciences; Esmaeil Farzaneh, Ardabil University Of Medical Sciences; Tahmineh Afsharian, Private Physician P313 Paraquat toxic effects are beyond the respiratory system: evidence for hepato- and renotoxicity
Hassan Malekinejad, Urmia University P303 Effect of Exposure to Bile Salts on Urea Formation in Sandwich-Cultured Rat Hepatocytes
Sagnik Chatterjee, Katholieke Universiteit Leuven; Patrick Augustijns, Katholieke Universiteit Leuven; Pieter Annaert, Katholieke Universiteit Leuven P318 Transcriptomics analysis of the Artemisinin stress response in mouse embryonic stem cells
M. Raamsman-Ossevoort, Leiden University, Leiden/Amsterdam Center for Drug Research; J. Carreras Puigvert, Leiden University, Leiden/Amsterdam Center for Drug Research; B. Van de Water, Leiden University, Leiden/Amsterdam Center for Drug Research P312 Nephrotoxicity Induced by Fenthion IN ADULT RATS AND THEIR SUCKLING PUPS
Mediha Sefi, Faculty of sciences P302 Deuterium insertion approach to reduce metabolism-mediated liabilities: Integration of biotransformation results and structural modification into potential toxicity findings
Amin Kamel, Novartis Institutes for BioMedical Research; Mithat Gunduz, Novartis Institutes for BioMedical Research; Natalie Dales, Novartis Institutes for BioMedical Research; Clayton Springer, Novartis Institutes for BioMedical Research; Suzie Ferreira, Novartis Institutes for BioMedical Research; Franco Lombardo, Novartis Institutes for BioMedical Research; Shawn Harriman, Novartis Institutes for BioMedical Research P317 TNF-alpha enhances cisplatin-induced renal injury via the JNK and NF-kB pathways
Giulia O.E. Benedetti, Lacdr; J. Meerman, Lacdr; B. van de Water, Lacdr; M. de Graauw, Lacdr P311 Metabolic Activation of Chlorogenic Acid in vitro and in vivo
Xiaoyan Chen, Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Cen Xie, Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Tao Yuan, Shanghai Institute of Materia Medica, Chinese Academy of Sciences; Dafang Zhong, Shanghai Institute of Materia Medica, Chinese Academy of Sciences P315 Precision-cut liver slices as an ex vivo model to study idiosyncratic hepatotoxicity in mouse and human
Mackenzie Hadi, University of Groningen; Yixi Chen, University of Groningen; Harry Emmen, NOTOX B.V.; Miranda Stitzinger, NOTOX B.V.; Geny Groothuis, University of Groningen P305 Erdosteine has dual effects on haemostasis via its different metabolites in young rats
Süleyman Oktar, Medical Faculty of Mustafa Kemal University; Vefik Arica, Medical Faculty of Mustafa Kemal University; Murat Tutanc, Medical Faculty of Mustafa Kemal University; Oktay Hasan Ozturk, Medical Faculty of Mustafa Kemal University P296 Acute disruption of bone marrow hematopoietic progenitor cells by benzo(a)pyrene (BP) is reversed by processes dependent on Ah Receptor activation
Alhaji U. N'Jai, University of Wisconsin Madison; Michele Larsen, University of Wisconsin Madison; Charles J. Czuprynski, University of Wisconsin Madison; Colin R. Jefcoate, University of Wisconsin Madison P310 Mechanism of Hepatoprotective Effect of Tamoxifen Against Drug-induced Liver Injury
Tsuyoshi Yokoi, Faculty of Pharmaceutical Sciences, Kanazawa University; Yukitaka Yoshikawa, Faculty of Pharmaceutical Sciences, Kanazawa University; Yasuyuki Toyoda, Faculty of Pharmaceutical Sciences, Kanazawa University; Satonori Higuchi, Faculty of Pharmaceutical Sciences, Kanazawa University; Tohru Tsukui, Research Center for Genomic Medicine; Koichi Tsuneyama, Department of Diagnostic Pathology; Tatsuki Fukami, Faculty of Pharmaceutical Sciences, Kanazawa University; Miki Nakajima, Faculty of Pharmaceutical Sciences, Kanazawa University P307 Exploiting the Third Dimension for Predicting Drug Induced in vitro Nephrotoxicity
Sreenivasa Ramaiahgari, Leiden University; Bob van de Water, LACDR, Leiden University; Leo Price, Leiden University P309 Influence of valproate on the levels of tri- and diphosphate nucleotides in rat liver tissues
Paula B. M. Luis, Faculdade de Farmácia, Universidade de Lisboa; Lodewijk IJlst, Laboratory Genetic Metabolic Diseases, Dep. Clinical Chemistry and Pediatrics, AMC, University of Amsterdam, The Netherlands; Jeroen Roelofsen, Amsterdam Medical Centre, University of Amsterdam; André B.P. van Kuilenburg, Amsterdam Medical Centre, University of Amsterdam; Marinus Duran, Laboratory Genetic Metabolic Diseases, Dep. Clinical Chemistry and Pediatrics, AMC, University of Amsterdam, The Netherlands; Isabel Tavares de Almeida, Faculdade de Farmácia, Universidade de Lisboa; Ronald J.A. Wanders, Laboratory Genetic Metabolic Diseases, Dep. Clinical Chemistry and Pediatrics, AMC, University of Amsterdam, The Netherlands; Margarida F.B. Silva, Faculdade de Farmácia, Universidade de Lisboa P300 Bioactivation of Glafenine by Human Liver Microsomes and Peroxidases: Identification of Electrophilic Iminoquinone Species and Glutathione Conjugates
Bo Wen, Hoffmann-La Roche; Yanzhou Liu, Roche Palo Alto; Tian J. Yang, Hoffmann-La Roche Inc. P306 Evidences of covalent adduct formation of quinoline compounds and their phase I metabolites with glutathione and N-acetyl cysteine
Bhagwat Prasad, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India; Amit Garg, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India; Saranjit Singh, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India; Rahul Jain, National Institute of Pharmaceutical Education and Research (NIPER), SAS Nagar 160062, Punjab, India P304 Effect of Phenobarbital on the Cytotoxicity of Valproic Acid and 2-Ene-Valproic Acid in Sandwich Cultures of Rat Hepatocytes
Jayakumar Surendradoss, Univ of British Columbia; Stoyan Karagiozov, Univ of British Columbia; Thomas K. H. Chang, Univ of British Columbia; Frank S. Abbott, Univ of British Columbia P314 Potential biomarker for the assessment of hepatotoxicity induced by metabolic activation of pyrrolizidine alkaloids
Ge Lin, The Chinese University of Hong Kong; Na Li, The Chinese University of Hong Kong; Mi Li, The Chinese University of Hong Kong; Wood-Yee Chan, The Chinese University of Hong Kong; Peter P. Fu, National Center for Toxicological Research; Hong-Xi Xu, Hong Kong Jockey Club Institute of Chinese Medicine |
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Yazan Administrator
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Extrahepatic metabolism P217 Skin metabolism review
Joan Eilstein, L'Oréal Research; Guillaume Lereaux, L'Oréal Research; Jean-Roch Meunier, L'Oréal Research; Jacques Leclaire, L'Oréal Research; Duché Daniel, L'Oréal Research P212 CYP2A6/2A13 and CYP1A1/1B1 activity is conserved in cultures of differentiated primary human tracheobronchial epithelial cells
Nik Newland, British American Tobacco; Andrew Baxter, British American Tobacco; Katherine Hewitt, British American Tobacco; Emmanuel Minet, British American Tobacco P218 The newly discovered molybdenum-containing enzyme mARC is a novel extrahepatic drug metabolizing enzyme
Bernd Clement, Universitat Kiel; Antje Havemeyer, Universitat Kiel; Carmen Krischkowski, Universitat Kiel; Florian Bittner, TU Braunschweig; Ralf R. Mendel, TU Braunschweig P211 Characterization of N-Acetyl and Glutathione S-Transferase Activities in Skin and Reconstructed Human Skin Models
Joan Eilstein, L'Oréal Research; Guillaume Lereaux, L'Oréal Research; Edwige Daronnat, L'Oréal Research; Jean-Roch Meunier, L'Oréal Research; Jacques Leclaire, L'Oréal Research; Daniel Duche, L'Oréal Research P210 Characterization of Esterase, Glucuronyl and Sulfo transferase Activities in Skin and Reconstructed Human Skin Models
Guillaume Lereaux, L'Oréal Research; Joan Eilstein, L'Oréal Research; Jean-Roch Meunier, L'Oréal Research; Jacques Leclaire, L'Oréal Research; Daniel Duche, L'Oréal Research P214 EFFECTS of Aspirin Overdose ON Balf VEGF of Endotoxemic Rats
Ozlem Aydin, Eskisehir Osmangazi University, Faculty of Medicine,; Neslihan Tekin, Eskisehir Osmangazi University, Faculty of Medicine,; Tayfun Aydin, Dumlupinar University, Faculty of Medicine, Health Research and Training Hospital; Halide E. Temel, Anadolu University, Faculty of Pharmacy; Dilek Burukoglu, Eskisehir Osmangazi University, Faculty of Medicine,; Erinç Aral, Eskisehir Osmangazi University, Faculty of Medicine,; Fahrettin Akyuz, Eskisehir Osmangazi University, Faculty of Medicine, P216 Intestinal First-pass Metabolism of TNP
Hua Li, Beijing Institute of Pharmacology and Toxicology; Jing-ting Deng, Beijing Institute of Pharmacology and Toxicology; Xiao-mei Zhuang, Beijing Institute of Pharmacology and Toxicology P213 Cytochrome-P450 Activities in Rat Brain Microsomal Preparations
Nicola Caradonna, SienaBiotech SpA; Massimo Valoti, University of Siena; Giulia Franco, University of Siena; Stefania Dragoni, University of Siena; Ugo Zanelli, Siena Biotech SpA; Goran Westerberg, SienaBiotech SpA P215 Flavin Monooxygenases (FMOs) and Species Differences in Pulmonary Metabolism
Mark D. Wrona, Merck Frosst Canada & Co.; Amandine Chefson, Merck Frosst Canada & Co.; Jean-François Chiasson, Merck Frosst Canada & Co.; France Landry, Merck Frosst Canada & Co.; Jean-François Lévesque, Merck Frosst Canada & Co.; Richard Tschirret-Guth, Merck Frosst Canada & Co.; Leanne L. Bedard, Merck Frosst Canada & Co. |
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Yazan Administrator
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Gene expression and regulation P219 Activated Sterol Regulatory Element-Binding Protein-2 Suppresses Hapatocyte Nuclear Factor-4-Mediated Cyp3a11 Expression in Mouse Liver
Shin-ichi Inoue, Graduate School of Pharmaceutical Sciences, Tohoku University; Kouichi Yoshinari, Graduate School of Pharmaceutical Sciences, Tohoku University; Mika Sugawara, Graduate School of Pharmaceutical Sciences, Tohoku University; Yasushi Yamazoe, Graduate School of Pharmaceutical Sciences, Tohoku University P220 Activity of Aryl hydrocarbon receptor (AhR) in the placental trophoblast and expression of AhR and its translocator ARNT expression in rat and human placentas during pregnancy
Lucie Stejskalova, Faculty of Pharmacy, Charles University; Lenka Vecerova, Faculty of Pharmacy, Charles University; Laura Messa Perez, Faculty of Pharmacy, Charles University; Lenka Hahnova, Faculty of Pharmacy, Charles University; Petr Nachtigal, Faculty of Pharmacy, Charles University; Radim Vrzal, Faculty of Science, Palacky University; Zdenek Dvorak, Faculty of Science, Palacky University; Petr Pavek, Faculty of Pharmacy, Charles University P221 Association of the DNA-PK Component, KU, with IKAROS Isoforms and ITS EFFECTS On DNA Binding Affinity
Zahide Ozer, CHLA(Children Hospital Los Angeles)-USA P222 Automated imaging, quantification and classification of NF-kB and Nrf2 responses to identify adverse drug reactions in HepG2 cells
Bram Herpers, LACDR; Zi Di, LACDR; Lisa E. Fredriksson, LACDR; Bob van de Water, LACDR P223 Effect of Promoter Region Polymorphisms in N-Acetyltransferase 2 (NAT2) Phenotype
Rika Yuliwulandari, University of Tokyo P224 Expression of wild type p53 is induced in HepG2 cells by a Sri Lankan herbal decoction comprised of Nigella sativa (seeds), Hemidesmus indicus (roots), and Smilax glabra (rhizome)
Sameera R. Samarakoon, Institute of Biochemistry, Molecular Biology & Biotechnology; Prasanna B. Galhena, Faculty of Medicine, University of Kelaniya; M. Ira Thabrew, Institute of Biochemistry, Molecular Biology, and Biotechnology, University of Colombo; Kamani H. Tennekoon, Institute of Biochemistry, Molecular Biology, and Biotechnology, University of Colombo P225 Med25 as a coactivator of HNF4α, reveals vital role in RNA Polymerase II recruitment and defective drug metabolism in human liver
Sailesh Surapureddi, National Institute for Environmental Health Sciences, National Institutes of Health; Ritu Rana, National Institute for Environmental Health Sciences, National Institutes of Health; Joyce Goldstein, National Institute for Environmental Health Sciences, National Institutes of Health P226 Minor changes in 2,4,6-tryphenyldioxane-1,3 inducer structure cause changes in CAR mediated CYP2B induction
Vladimir Pustylnyak, Institute of MolBiol & Bioph SB RAMS; Andrey Yarushkin, Institute of MolBiol & Bioph SB RAMS; Ekaterina Kachaylo, Novosibirsk State University; Nikolay Slynko, Institute of Cytology and Genetics; Lyudmila F. Gulyaeva, Institute of MolBiol and Bioph SB RAMS P227 The Influence of Extracellular Signal-Regulated Protein Kinase (ERK) on Pregnane X Receptor-Mediated Expression of CYP3A4 and MDR1 Genes in Hepatocellular Carcinoma Cell Lines and in Primary Human Hepatocytes
Michal Bitman, Faculty of Pharmacy, Charles University; Radim Vrzal, Faculty of Science, Palacky University; Zdenek Dvorak, Faculty of Science, Palacky University; Lucie Stejskalova, Faculty of Pharmacy, Charles University; Petr Pavek, Faculty of Pharmacy, Charles University |
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Yazan Administrator
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Enzyme inhibition/inactivation P191 COMT EXPRESSION and Activity AFTER Chronic Administration of Bia 9-1067 to Wistar Rats
Maria Joao Bonifacio, BIAL; Leonel Torrão, BIAL; Maria João Pinho, Instituto de Farmacologia e Terapêutica, Faculdade de Medicina, Universidade do Porto; Lyndon Wright, BIAL; Patrício Soares-da-Silva, BIAL P198 Identification Of Time-Dependant CYP450 3A4 Inhibitors Using Cryopreserved Hepatocytes
Ralf R.H. Lotz, Boehringer Ingelheim Pharma GmbH&Co KG P199 Inhibition of Human Cytochrome P450 Isoforms by Mitragyna speciosa Extracts
Sabariah Ismail, Universiti Sains Malaysia; Nur Aziah Hanapi, Universiti Sains Malaysia; Juzaili Azizi, Universiti Sains Malaysia; Sharif Mahsufi Mansor, Universiti Sains Malaysia; Roziahanim Mahmud, Universiti Sains Malaysia P194 Effects of Some Indole Derivates On Aldose Reductase Enzyme Activity
Erdem Kursun, Ankara University Faculty of Science; Gökçe Gurkok, Ankara University Pharmacy Faculty; Sibel Suzen, Ankara University Pharmacy Faculty; Net Evcimen, Ankara University Pharmacy Faculty; Özlem Yildirim, Ankara University Faculty of Science P195 Evaluation Of Single Point And IC50 Shift Assays For Measuring Time-Dependent Inhibition Of Drug Discovery Compounds
Katie Fox, Cyprotex; Rosey Pearson, Cyprotex; Philip Butler, Cyprotex; Clive Dilworth, Cyprotex P188 Cadmium Alters the Biotransformation of Carcinogenic Aromatic Amines by Xenobiotic-Metabolizing Enzymes Arylamine N-Acetyltransferases
Nilusha Ragunathan, Universite Paris Diderot; Julien Dairou, Universite Paris Diderot; Elodie Sanfins, Universite Paris Diderot; Florent Busi, Universite Paris Diderot; Christophe Noll, Universite Paris Diderot; Nathalie Janel, Universite Paris Diderot; Jean-Marie Dupret, Universite Paris Diderot; Fernando Rodrigues-Lima, Universite Paris Diderot P196 Human xenobiotic-metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1) is irreversibly inhibited by inorganic mercury (Hg2+) and methylmercury (CH3Hg+)
Nilusha Ragunathan, Universite Paris Diderot; Florent Busi, Universite Paris Diderot; Jean-Marie Dupret, Universite Paris Diderot; Fernando Rodrigues-Lima, Universite Paris Diderot; Julien Dairou, Universite Paris Diderot P197 Identification of a novel carbamoyl glucuronide as a metabolism-dependent inhibitor of CYP2C8
Faraz Kazmi, XenoTech, LLC; Brian Smith, XenoTech, LLC; Mette G. Hvenegaard, H. Lundbeck A/S; Lene Bendahl, H. Lundbeck A/S; Amy Gipson, XenoTech, LLC; David Buckley, XenoTech, LLC; Brian Ogilvie, XenoTech, LLC; Andrew Parkinson, XenoTech, LLC P203 Pitfalls in the design of metabolism-dependent CYP inhibition (MDI) experiments with a dilution step: Inhibitor depletion by metabolism and/or microsomal binding leads to underestimation of the shifted IC50 value
David B. Buckley, XenoTech, LLC; Faraz Kazmi, XenoTech, LLC; Phyllis Yerino, XenoTech, LLC; Paul Toren, XenoTech, LLC; Jeff Holsapple, XenoTech, LLC; Brian W. Ogilvie, XenoTech, LLC; Brandy Paris, XenoTech, LLC; Andrew Parkinson, XenoTech, LLC P202 Methoxyalkyl-Guanidines and -Amidines as Inhibitors of Human DDAH-1
Jürke Kotthaus, Christian-Albrechts-University; Ina Lunk, Christian-Albrechts-University; Dennis Schade, Christian-Albrechts-University; Bernd Clement, Christian-Albrechts-University P207 Time-Dependent Inhibition of CYP2E1 by the Alcohol Cessation Agent Clomethiazole
David M. Stresser, BD Biosciences Discovery Labware; Eric T Gangl, BD Biosciences Discovery Labware; Elke S Perloff, BD Biosciences Discovery Labware; Andrew K Mason, BD Biosciences Discovery Labware; Andrew P Blanchard, BD Biosciences Discovery Labware; Sean Ekins, Collaborations In Chemistry; Shangara S Dehal, BD Biosciences Discovery Labware P193 Deoxyschizandrin Could Attenuate Cytochrome P450 3A4-Mediated Bioactivation of Gomisin A in Human Liver Microsomes
Yan-Yan Zhang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P201 Inhibitory potential of Chlormadinone acetate (CMA) on five important UDP-Glucuronosyltransferases in human liver
Ting Huang, Shanghai Institute of Planned Parenthood Research; Zhong-Ze Fang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Yan-Yan Zhang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P200 Inhibition of Human Liver Cytochrome P450 2C8 and 3A4 by Sanguinarine
Xiao-Yi Qi, Second Affiliated Hospital of Dalian Medical University, Dalian, China; Si-Cheng Liang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Guangbo Ge, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Zhong-Ze Fang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P206 Reversible inhibition of four important human liver cytochrome P450 enzymes by diethylstilbestrol
Yan Qing Qu, The Second Affiliated Hospital of Dalian Medical University; Zhong-Ze Fang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P190 Commonly used inhibitors of drug metabolizing enzymes: Do they also inhibit drug transporters?
Emile G. Plise, Genentech Inc; Jason S. Halladay, Genentech Inc; Jonathan Cheong, Genentech Inc; Jasleen Sodhi, Genentech Inc; Laurent Salphati, Genentech Inc P189 Cofactor Metal Levels and Enzyme Activities in Cisplatin-Treated Rats: Effect of Antioxidant Intervention
Suna Sabuncuoglu, Hacettepe University, Faculty of Pharmacy; Ayse Eken, Gulhane Military Medical Academy; Hilal Ozgunes, Hacettepe University, Faculty of Pharmacy; Ahmet Aydin, Yeditepe University, Faculty of Pharmacy; Hilmi Orhan, Ege University Faculty of Pharmacy P192 Cytochrome P450 time-dependent inhibition assays: Considerations for the preincubation step and data processing
Charles L. Crespi, BD Biosciences Discovery Labware; Elke S Perloff, BD Biosciences Discovery Labware; David M Stresser, BD Biosciences Discovery Labware P208 Utilization and Optimization of Cryopreserved Human Hepatocytes as a Model to Assess CYP450 Inhibition
LaHoma Easterwood, Invitrogen/Life Technology; Lee Robinson, Invitrogen/Life Technology; Ben Fontenot, Invitrogen/Life Technology; Jenny Smith, Invitrogen/Life Technology; Mike Shaw, Invitrogen/Life Technology; Jason Wright, Invitrogen/Life Technology P205 Rational Design of CYP2C9 Mechanism Based Inhibitors
Michael L. Schrag, ProPharma Services |
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