StatisticsÜyeler: 302
Haberler: 287
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Ziyaretçiler: 452249
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Yazan Administrator
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Environmental Toxicology P157 Determination of Benzene, Toluene, Ethyl Benzene and Xylenes in urine of exposed and non-exposed residents of Ankara
Emrah Dural, Institute of Forensic Medicine, Ankara University; Erhan Boran, Institute of Forensic Medicine, Ankara University; Betul Isiner, Institute of Forensic Medicine, Ankara University; Görkem Mergen, Institute of Forensic Medicine, Ankara University; Tülin Söylemezoglu, Institute of Forensic Medicine, Ankara University P158 Determination of Six Fungicides Using the Quick Easy Cheap Effective Rugged and Safe (QuEChERS) in Combination with LC in Food
Gül Özhan, Istanbul University; Buket Alpertunga, Istanbul University P159 Dioxin-induced Disorders in Fetal Steroidogenesis and Gonadotropin Formation: Minor Contribution of Oxidative Stress to the Damages and the Protective Effect of a Vitamin, a-Lipoic Acid
Takayuki Koga, Graduate School of Pharmaceutical Sciences, Kyushu University; Tomoki Takeda, Graduate School of Pharmaceutical Sciences, Kyushu University; Takumi Ishida, Graduate School of Pharmaceutical Sciences, Kyushu University; Yuji Ishii, Graduate School of Pharmaceutical Sciences, Kyushu University; Hideyuki Yamada, Graduate School of Pharmaceutical Sciences, Kyushu University P160 Do multiple cytochrome P450 isoforms contribute to the activation of the insecticide carbosulfan in human?
Khaled Abass, Institute of Biomedicine, University of Oulu; Petri Reponen, University of Oulu; Miia Turpeinen, Institute of Biomedicine, University of Oulu; Sampo Mattila, University of Oulu; Olavi Pelkonen, Institute of Biomedicine, University of Oulu P161 Dr. Azzaoui Fatima-Zahra
Fatima-Zahra Azzaoui, Unit of Clinic and Cognitive Neuroscience and Health, Laboratory of Biology and Health, Faculty of Science; Ahmed Ahami, Unit of Clinic and Cognitive Neuroscience and Health, Laboratory of Biology and Health, Faculty of Science P162 Embryotoxic and Teratogenic Effects of Roundup® Max on Rat Development
Ayþe, Cansýn. Aslý, Dürdane Geriþlioglu, Hacettepe University; Dürdane Kolankaya Sr., Hacettepe University P163 Experimental Study on the Effect of Roasting, Boiling and Microwaving Cooking Method on Enrofloxacin Residues in Edible Tissues of Poultry
Afshin Javadi, Islamic Azad University, Tabriz Branch,Tabriz, Iran; Seied Amin Khatibi, Islamic Azad University, Tabriz Branch,Tabriz, Iran; Hamid Mirzaie, Islamic Azad University, Tabriz Branch,Tabriz, Iran P164 Highly Elevated 7-Ethoxyresorufin O-deethylase (EROD) Activities in Flathead Mullet (Mugil cephalus) and Striped Red Mullet (Mullus surmuletus) from Zonguldak Harbour
Azra Bozcaarmutlu, Abant Izzet Baysal University; Canan Sapmaz, Abant Izzet Baysal University; Sema Gulen, Abant Izzet Baysal University; Emel Arinç, Middle East Technical University P165 In vivo Genotoxicity Assessment of Esbiothrin in Fish (Cyprinus carpio L., 1758) Using the Micronucleus Test and Comet Assay
Mahmut Selvi, Gazi University; Tolga Çavas, Uludag University; A.Caglan Karasu Benli, Gazi University; Burcu Kocak Memmi, Hacettepe University; Nilüfer Cinkilic, Uludag University; Aylin Sepici Dincel, Gazi University; Ozgur Vatan, Uludag University; Dilek Yilmaz, Uludag University; Rabia Sarikaya, Gazi University; Tolga Zorlu, Uludag University; Figen Erkoç, Gazi University P166 Preventive effect of magnesium on nickel hepatotoxicity and nephrotoxicity in albino (Wistar) rats
Zine Kechrid, University of Annaba, Annaba, Algeria P167 Protective role of ascorbic acid on lambdacyhalothrin-induced oxidative stress and alterations of acetylcholinesterase activity in the cerebellum of adult rats
Hamadi Fetoui, Laboratory of animal Physiology P168 Study of occupationnal hazards on human infertility
Bensoltane Samira, Faculty of medecine; Abdelaziz Amina, University of Badji Mokhtar, Faculty of sciences; Djekoun Mohamed, Faculty of sciences and ingeniery, 08 mai 1945 University; Loucif Wahida, Faculty of medecine; Berkat Faical, Faculty of medecine P170 The Epidemiologyic Study of Suicide in North West Of Iran
Esmaeil Farzaneh, Ardebil University of Medical Sciences, Ardabil, Iran; Iraj Sayadrezai, Ardabil university of medical sciences; Babak Mostafazadeh, Shaheed Beheshty University Of Medical Sciences; Farnaz nasl Seraji, Ardebil University of Medical Sciences, Ardabil, Iran P171 The impact of Propiconazole on the fertility in domestic rabbits
Mallem Leila, Faculty of medecine, university of Annaba; Boulakoud Mohamed Salah, University Badji Mokhtar- Annaba, Faculty of science P172 The mechanism of defects in sexual behavior by maternal exposure to dioxin: Focusing on gene expression in the pituitary and hypothalamus
Tomoki Takeda, Graduate School of Pharmaceutical sciences, Kyushu University; Misaki Fujii, Graduate School of Pharmaceutical sciences, Kyushu University; Junki Taura, Graduate School of Pharmaceutical sciences, Kyushu University; Midori Yamamoto, Nagasaki International University; Masaru Himeno, Nagasaki International University; Yuji Ishii, Graduate School of Pharmaceutical sciences, Kyushu University; Takumi Ishida, Graduate School of Pharmaceutical sciences, Kyushu University; Hideyuki Yamada, Graduate School of Pharmaceutical sciences, Kyushu University P173 The Role of CYP51 in Global Health
Michael R. Waterman, Center in Molecular Toxicology, Vanderbilt University School of Medicine; Galina I. Lepeshesheva, Center in Molecular Toxicology, Vanderbilt University School of Medicine P174 Toxicities of selected insecticides on the survival rate of Drosophila melanogaster (mwh x flr3) larvae
Burcu Kocak Memmi, Hacettepe University; Rabia Sarıkaya, Gazi University; Sibel Sümer, Hacettepe University; Figen Erkoç, Gazi University |
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Yazan Administrator
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Drug interaction P143 Application of Different In Vitro Systems for Prediction of In Vivo Induction Drug-Drug Interactions
Ian E. Templeton, University of Manchester; J. Brian Houston, University of Manchester; Aleksandra Galetin, University of Manchester P144 Effect of metronidazole on the pharmacokinetics of fexofenadine in healthsy subjects
Kyoung-Ah Kim, Anam Hospital, Korea University College of Medicine; Ji-Young Park, Anam Hospital, Korea University College of Medicine P145 Herb-Drug interaction: effect of isopeulustrin on the metabolism and pharmacokinetics of tetramethylpyrazine by in vivo and in vitro methods
Xin He, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine; Shan Feng, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine; Yuefei Wang, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine; Chao Li, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine; Jipeng Hou, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine; O. N. K. Martey, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine; Changxiao Liu, Tianjin Key laboratory of chemical and analysis of Chinese materia medica, Tianjin University of Traditional Chinese Medicine P146 In vitro inhibition and induction of human liver cytochrome P450 enzymes by NTBC and its metabolism in human liver microsomes
Jason N. Neat, XenoTech, LLC; Andrea Wolff, XenoTech, LLC; Faraz Kazmi, XenoTech, LLC; Pilar Prentiss, XenoTech, LLC; David Buckley, XenoTech, LLC; Elizabeth M. Wilson, Yecuris Corporation; John Bial, Yecuris Corporation; Cedo M. Bagi, Pfizer, Inc.; Markus Grompe, Yecuris Corporation; Andrew Parkinson, XenoTech, LLC P147 Nano-silver Particle “Mineral Supplement” Effects On Drug Metabolism
Michael R. Franklin, University of Utah; Laura B Hathaway, University of Utah; John G Lamb, University of Utah; Judy Raucy, Puracyp, Inc P148 Pharmacokinetic Interaction Between Ivabradine and Carbamazepine in Healthy Volunteers
Laurian Vlase, University of Medicine and Pharmacy Iuliu Hatieganu; Adina Popa, University of Medicine and Pharmacy Iuliu Hatieganu; Maria Neag, University of Medicine and Pharmacy Iuliu Hatieganu; Dana Muntean, University of Medicine and Pharmacy Iuliu Hatieganu; Sorin Leucuta, University of Medicine and Pharmacy Iuliu Hatieganu P149 Physiologically-based pharmacokinetic modelling approach to assess the uptake transporter-mediated drug-drug interaction potential of cyclosporine
Michael Gertz, University of Manchester; J. Brian Houston, University of Manchester; Aleksandra Galetin, University of Manchester P150 Predicting Transporter-Mediated Drug-Drug Interactions Based on the B-CLEAR®-Rapid Transport Screen in Sandwich-Cultured Hepatocytes
Jin Kyung Lee, Qualyst Inc; Cassandra H. Perry, Qualyst, Inc.; Chris Parsons, Qualyst, Inc.; Robert L. St. Claire III, Qualyst, Inc.; Kenneth R. Brouwer, Qualyst, Inc. P151 Predictions of metabolic Drug Drug Interactions after Intravenous administration: impact of hepatic extraction ratio
Cristina Lopez, Aureus Pharma; Patrice Dehanne, Aureus Pharma; Estelle Rapine, Aureus Pharma; Olivier Barberan, Aureus Pharma; Xavier Boulenc, Sanofi-Aventis P152 Seizurogenic Effects of Low-dose Naloxone in Tramadol Overdose
Esmaeil Farzaneh, Ardebil University of Medical Sciences, Ardabil, Iran; Babak Mostafazadeh, Shaheed Beheshty University Of Medical Sciences; Farnaz nasl Seraji, Ardebil University of Medical Sciences, Ardabil, Iran; Iraj sayad Rezai, Ardebil University of Medical Sciences, Ardabil, Iran P153 Sequential Arabinosylcytosin with or without Fludarabine in Paracmastic Patients of Acute Myeloid Leukemia
Zhang Hong, Tongji Hospital of Tongji University P154 The impact of PBPK modeling on prediction of drug drug interaction potential of a candidate drug with non linear pharmacokinetics
Jan Snoeys, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V.; Jos Van Houdt, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V.; Vikash Sinha, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V.; Geert Mannens, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V.; Patrick Sterkens, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V.; Nancy Van Osselaer, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V.; Mario Monshouwer, Johnson & Johnson Pharmaceutical Research and Development, a division of Janssen Pharmaceutica N.V. P155 The Pharmacokinetic Interaction Between JBP485 And Cephalexin In Vivo And In Vitro
Kexin Liu, Dalian Medical University; Jian Zhang, Dalian Medical University; Changyuan Wang, Dalian Medical University; Qi Liu, Dalian Medical University; Qiang Meng, Dalian Medical University; Xinjin Guo, Dalian Medical University; Jian Cang, Dalian Medical University; Taiichi Kaku, Bioproducts Industry Co. Ltd. P156 The POSSIBLE Interaction BETWEEN SLC TRANSPORTER Mediated UPTAKE and FDA Recommended Potent CYP Inhibitors
Yasuhisa Adachi, Sekisui Medical Co., Ltd.; Miki Fujishima, Sekisui Medical Co., Ltd.; Takami Sarashina, Sekisui Medical Co., Ltd.; Teruhiko Yanagisawa, Sekisui Medical Co., Ltd.; Shinsuke Aoyama, Sekisui Medical Co., Ltd.; Yoshihiro Ohzone, Sekisui Medical Co., Ltd.; Shin-ichi Ninomiya, Sekisui Medical Co.,Ltd. |
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Yazan Administrator
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Differences in metabolism (species, gender, age, diseases) P96 Comarative metabolism of albendazole in finfish species
Badar Shaikh, US Food & Drug Administration; Nathan G. Rummel, US Food & Drug Administration; Charles Gieseker, US Food & Drug Administration; Renate Reimschuessel, US Food & Drug Administration; Joseph Kawalek, Food and Drug Administration P97 Comparison of the Formation Kinetics of Hydroxymethyltolbutamide in Chimpanzee, Cynomolgus Monkey, Marmoset, Rhesus Monkey and Human Liver Microsomes
James Grace, Bristol-Myers Squibb Co; Michael Sinz, Bristol-Myers Squibb Co; Kimberley Lentz, Bristol-Myers Squibb P98 Evaluation of the IL-6-Mediated Suppression of Cytochrome P450 and Transporter Activities in Human Cryopreserved Hepatocytes
Brigitte Gerin, UCB Pharma SA; Sylvie Dell'Aiera, UCB Pharma SA; Annick Cauvin, UCB Pharma SA; Helen Neale, UCB Pharma SA; Hilmar Boekens, UCB Pharma SA; Steven Smith, UCB Pharma SA; Hugues Chanteux, UCB Pharma SA P99 Influence of Gender and Ethnicity on Drug Metabolizing Enzyme Activity in Human Hepatocytes
Matthew Sherman, CellzDirect/Life Technologies; Cornelia Smith, CellzDirect/Life Technologies; Heather Rollins, CellzDirect/Life Technologies; Jeanine Fogarty, CellzDirect/Life Technologies; Jasminder Sahi, CellzDirect/Life Technologies P100 Interspecies differences acetylation of (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1H-imidazole-2(3H)-thione hydrochloride
Ana I. Loureiro, BIAL; Carlos Fernandes-Lopes, BIAL; Lyndon Wright, BIAL; Patricio Soares-da-Silva, BIAL P101 Ontogeny of Glutathione Transferase Z1 (GSTZ1) Expression and Activity with Dichloroacetate in Human Liver Cytosol
Margaret O. James, University of Florida; Ronald N. Hines, Medical College of Wisconsin & Children's Hospital & Health System; Yuan Gu, University of Florida; Wenjun Li, University of Florida; Taimour Langaee, University of Florida; Peter W. Stacpoole, University of Florida P102 The Role of Lipid Peroxidation and Antioxidant Protection Systems of Kidneys in Rabbits' Predisposition Towards Gentamicine Nephrotoxicity
Tatiana V. Bushma, Grodno State Medical University; Kiryl M. Bushma, Grodno State Medical University |
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Yazan Administrator
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DNA Damage and Repair P114 Combined Cytotoxic Effects of Heterocyclic Aromatic Amines and Polycyclic Aromatic Hydrocarbon on a Human Intestinal Cell Line
Natsuko Takakura, AFSSA; Ludovic Le Hégarat, AFSSA; Valérie Fessard, AFSSA P115 DNA damage in human mesenchymal stem cells and human bone marrow cells: a comparative study
Aminat Chausheva, Research Centre for Medical Genetics RAMS; Victoria Nikitina, Research Centre for Medical Genetics RAMS; Aliy Zhanataev, State Zakusov's Research Institute of Pharmacology of RAMS,; Nikolay Bochkov, Research Centre for Medical Genetics RAMS P116 Mapping DNA damage response through RNAi screening and systems approach
Erik HJ Danen, LACDR, Leiden University; Bob van de Water, LACDR, Leiden University; Jordi Carreras Puigvert, LACDR, Leiden University; Louise Von Stechow, LACDR, Leiden University; Ram Siddappa, LACDR, Leiden University; Leon Mullenders, LUMC; Harry Vrieling, LUMC P117 Melatonin Decreases DNA Fragmantation and Oxidative STRESS PARAMETERS of Gastrointestinal Mucosa
Kazime G. Akbulut, Gazi University School of Medicine; Hakan Akbulut, Ankara University School of Medicine; Nalan Akgun, Ankara University School of Medicine |
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Yazan Administrator
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Conjugation reactions and enzymes P43 A Novel Method for the Production of N- and O-Glucuronides Using Recombinant Fission Yeast (Schizosaccharomyces pombe)
Daniela Buchheit, PomBioTech GmbH; Calin-Aurel Dragan, PomBioTech GmbH; Matthias Bureik, PomBioTech GmbH P44 Casodex Up-Regulates The Expression Of The Androgens Inactivating Enzymes UDP-Glucuronosyltransferases 2B15 And 2B17 Expression In Prostate Cancer Cells
Laurent Grosse, CHUQ Research Center and Faculty of Pharmacy, University Laval; Sophie Paquet, CHUQ Research Center and Faculty of Pharmacy, University Laval; Alain Belanger, CHUQ Research Center and Faculty of Pharmacy, University Laval; Olivier Barbier, CHUQ Research Center and Faculty of Pharmacy, University Laval P45 Comparison of biotransformation of hydroxylated warfarins (OHWars) by human sulfotransferases (SULTs) and UDP-glucuronosyltransferases (UGTs)
Anna Radominska-Pandya, Univ of Arkansas for Med Sci; Josie L. Falany, University of Alabama at Birmingham; Ian T. Cook, University of Alabama at Birmingham; Stacie M. Bratton, Univ of Arkansas for Med Sci; Vi-Huyen Le, AR Public Health Laboratory; Kan Hui Yiew, Univ of Arkansas for Med Sci; Anna Gallus-Zawada, Univ of Arkansas for Med Sci; Charles N. Falany, University of Alabama at Birmingham; Jeffery H. Moran, AR Public Health Laboratory P46 Development of glucuronide preparation system for xenobiotic metabolites using genetically enginerred budding yeast
Shinichi Ikushiro, Toyama Prefectural University; Yuuka Masuyama, Toyama Prefectural University; Kaori Yasuda, Toyama Prefectural University; Masaki Kamakura, Toyama Prefectural University; Toshiyuki Sakaki, Toyama Prefectural University P47 Dichloroacetic acid protects against acetaminophen toxicity in mice
Angelo Theodoratos, John Curtin School of Medical Research; Anneke Blackburn, John Curtin School of Medical Research; Jean Cappello, John Curtin School of Medical Research; Philip Board, John Curtin School of Medical Research P48 Glucuronidation of arbidol: identification of human UDP-glucuronosyltransferases and interaction potential
Zhong-Ze Fang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P49 Identification of UDP-Glucuronosyltransferases involved in human hepatic glucuronidation of diethylstilbestrol
Liangliang Zhu, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Guangbo Ge, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Huixin Liu, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences; Ling Yang, Laboratory of Pharmaceutical Resource Discovery, Dalian Institute of Chemical Physics, Chinese Academy of Sciences P50 Improvement of In Vitro Approach to Study UDP-Glucuronosyltransferases 1A1 and 1A9 by Comparison of Absolute Protein Quantification and Metabolic Activity Measured Using Estradiol and Propofol as Selective Probe Substrates
Staffan Thorén, AstraZeneca R&D Södertälje; Wojciech Krol, University of North Carolina at Chapel Hill; Marie Wallin, AstraZeneca R&D Södertälje; Philip C. Smith, University of North Carolina at Chapel Hill; Maria Ribadeneira, AstraZeneca R&D Wilmington; Diansong Zhou, AstraZeneca; Pawel Baranczewski, AstraZeneca R&D Södertälje P51 Influence of Assays Conditions to Glucuronidation Activity in Vitro: Psilocin Study
Nenad Manevski, Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Helsinki University; Mika Kurkela, Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Finland; Camilla Höglund, Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Finland; Timo Mauriala, Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Finland; Michael H. Court, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts; Jari Yli-Kauhaluoma, Division of Pharmaceutical Chemistry, Faculty of Pharmacy, Helsinki University; Moshe Finel, Centre for Drug Research, Faculty of Pharmacy, University of Helsinki, Finland P52 Kinetic and Enzymatic Characterisation of Human Hepatic R- and S- Lorazepam Glucuronidation
Verawan Uchaipichat, Khon Kaen University; Chuthamanee Suthisisang, Mahidol University; Peter I. Mackenzie, Flinders University; John O. Miners, Flinders Univ Sch of Med P53 Metabolic Capacity of UDP-glucuronosyltransferase in Rat Brain
Kuniyuki Imai, Meijo University; Miki Katoh, Meijo University; Yuya Kondo, Meijo University; Masayuki Nadai, Meijo University P54 Phylogeny of arylamine N-acetyltransferases in fungi
Marta Martins, Universite Paris Diderot; Julien Dairou, Universite Paris Diderot; Fernando Rodrigues-Lima, Universite Paris Diderot; Jean-Marie Dupret, Universite Paris Diderot; Philippe Silar, Universite Paris Diderot P55 Prediction of in vivo drug-drug interactions involving UDP-glucuronosyltranferases using DDI Predict 2009® application
Patrice Dehanne, Aureus Pharma; Estelle Rapine, Aureus Pharma; Olivier Barberan, Aureus Pharma; Cristina Lopez, Aureus Pharma P56 Regional and Sex Differences in Expression of Ugt1a Subfamily in Rat Brain
Miki Katoh, Meijo University; Kuniyuki Imai, Meijo University; Yuya Kondo, Meijo University; Masayuki Nadai, Meijo University P57 Role of Human Glutathione S-Transferases on the Inactivation of Reactive Drug METABOLITES of Clozapine
Sanja Dragovic, Vrije Universiteit; Jan Simon Boerma, Vrije Universiteit; Laura van Bergen, Vrije Universiteit; Nico P. E. Vermeulen, Vrije Universiteit; Jan N. M. Commandeur, Vrije Universiteit P59 UGT2A2: a human polymorphic UDP-glucuronosyltransferase with unusual properties
Nina Sneitz, University of Helsinki; Xiuling Zhang, Wadsworth Center, NYSDOH; Xinxin Ding, Wadsworth Center, NYSDOH; Michael H. Court, Tufts Univ; Moshe Finel, University of Helsinki |
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