EC 6. Ligases
EC 6.1 Forming Carbon-Oxygen Bonds
EC 6.1.1 Ligases Forming Aminoacyl-tRNA and Related Compounds

EC 6.1.1.1 tyrosine—tRNA ligase
EC 6.1.1.2 tryptophan—tRNA ligase
EC 6.1.1.3 threonine—tRNA ligase
EC 6.1.1.4 leucine—tRNA ligase
EC 6.1.1.5 isoleucine—tRNA ligase
EC 6.1.1.6 lysine—tRNA ligase
EC 6.1.1.7 alanine—tRNA ligase
EC 6.1.1.8 deleted
EC 6.1.1.9 valine—tRNA ligase
EC 6.1.1.10 methionine—tRNA ligase
EC 6.1.1.11 serine—tRNA ligase
EC 6.1.1.12 aspartate—tRNA ligase
EC 6.1.1.13 D-alanine-poly(phosphoribitol) ligase
EC 6.1.1.14 glycine—tRNA ligase
EC 6.1.1.15 proline—tRNA ligase
EC 6.1.1.16 cysteine—tRNA ligase
EC 6.1.1.17 glutamate—tRNA ligase
EC 6.1.1.18 glutamine—tRNA ligase
EC 6.1.1.19 arginine—tRNA ligase
EC 6.1.1.20 phenylalanine—tRNA ligase
EC 6.1.1.21 histidine—tRNA ligase
EC 6.1.1.22 asparagine—tRNA ligase
EC 6.1.1.23 aspartate—tRNAAsn ligase
EC 6.1.1.24 glutamate—tRNAGln ligase
EC 6.1.1.25 lysine—tRNAPyl ligase
EC 6.1.1.26 pyrrolysine—tRNAPyl ligase
EC 6.1.1.27 O-phosphoserine—tRNA ligase

EC 6.1.2 Acid—Alcohol Ligases (ester synthases)

EC 6.1.2.1 D-alanine—(R)-lactate ligase

EC 6.2 Forming Carbon-Sulfur Bonds

EC 6.2.1 Acid-Thiol Ligases

EC 6.2.1.1 acetate—CoA ligase
EC 6.2.1.2 butyrate—CoA ligase
EC 6.2.1.3 long-chain-fatty-acid—CoA ligase
EC 6.2.1.4 succinate—CoA ligase (GDP-forming)
EC 6.2.1.5 succinate—CoA ligase (ADP-forming)
EC 6.2.1.6 glutarate—CoA ligase
EC 6.2.1.7 cholate—CoA ligase
EC 6.2.1.8 oxalate—CoA ligase
EC 6.2.1.9 malate—CoA ligase
EC 6.2.1.10 acid—CoA ligase (GDP-forming)
EC 6.2.1.11 biotin—CoA ligase
EC 6.2.1.12 4-coumarate—CoA ligase
EC 6.2.1.13 acetate—CoA ligase (ADP-forming)
EC 6.2.1.14 6-carboxyhexanoate—CoA ligase
EC 6.2.1.15 arachidonate—CoA ligase
EC 6.2.1.16 acetoacetate—CoA ligase
EC 6.2.1.17 propionate—CoA ligase
EC 6.2.1.18 citrate—CoA ligase
EC 6.2.1.19 long-chain-fatty-acid—luciferin-component ligase
EC 6.2.1.20 long-chain-fatty-acid—[acyl-carrier-protein] ligase
EC 6.2.1.21 covered by EC 6.2.1.30
EC 6.2.1.22 [citrate (pro-3S)-lyase] ligase
EC 6.2.1.23 dicarboxylate—CoA ligase
EC 6.2.1.24 phytanate—CoA ligase
EC 6.2.1.25 benzoate—CoA ligase
EC 6.2.1.26 o-succinylbenzoate—CoA ligase
EC 6.2.1.27 4-hydroxybenzoate—CoA ligase
EC 6.2.1.28 3α,7α-dihydroxy-5β-cholestanate—CoA ligase
EC 6.2.1.29 deleted now EC 6.2.1.7
EC 6.2.1.30 phenylacetate—CoA ligase
EC 6.2.1.31 2-furoate—CoA ligase
EC 6.2.1.32 anthranilate—CoA ligase
EC 6.2.1.33 4-chlorobenzoate—CoA ligase
EC 6.2.1.34 trans-feruloyl-CoA synthase
EC 6.2.1.35 ACP-SH:acetate ligase
EC 6.2.1.36 3-hydroxypropionyl-CoA synthase

EC 6.3 Forming Carbon-Nitrogen Bonds

EC 6.3.1 Acid-Ammonia (or Amine) Ligases (Amide Synthases)

EC 6.3.1.1 aspartate—ammonia ligase
EC 6.3.1.2 glutamate—ammonia ligase
EC 6.3.1.3 now EC 6.3.4.13
EC 6.3.1.4 aspartate—ammonia ligase (ADP-forming)
EC 6.3.1.5 NAD+ synthase
EC 6.3.1.6 glutamate—ethylamine ligase
EC 6.3.1.7 4-methyleneglutamate—ammonia ligase
EC 6.3.1.8 glutathionylspermidine synthase
EC 6.3.1.9 trypanothione synthase
EC 6.3.1.10 adenosylcobinamide-phosphate synthase
EC 6.3.1.11 glutamate—putrescine ligase
EC 6.3.1.12 D-aspartate ligase)
EC 6.3.1.13 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-α-D-glucopyranoside ligase
EC 6.3.1.14 diphthine—ammonia ligase

EC 6.3.2 Acid—Amino-Acid Ligases (Peptide Synthases)

EC 6.3.2.1 pantoate—β-alanine ligase
EC 6.3.2.2 glutamate—cysteine ligase
EC 6.3.2.3 glutathione synthase
EC 6.3.2.4 D-alanine—D-alanine ligase
EC 6.3.2.5 phosphopantothenate—cysteine ligase
EC 6.3.2.6 phosphoribosylaminoimidazolesuccinocarboxamide synthase
EC 6.3.2.7 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—L-lysine ligase
EC 6.3.2.8 UDP-N-acetylmuramate—L-alanine ligase
EC 6.3.2.9 UDP-N-acetylmuramoylalanine—D-glutamate ligase
EC 6.3.2.10 UDP-N-acetylmuramoylalanyl-tripeptide—D-alanyl-D-alanine ligase
EC 6.3.2.11 carnosine synthase
EC 6.3.2.12 dihydrofolate synthase
EC 6.3.2.13 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate—2,6-diaminopimelate ligase
EC 6.3.2.14 2,3-dihydroxybenzoate—serine ligase
EC 6.3.2.15 deleted, due to EC 6.3.2.10
EC 6.3.2.16 D-alanine—alanyl-poly(glycerolphosphate) ligase
EC 6.3.2.17 tetrahydrofolate synthase
EC 6.3.2.18 γ-glutamylhistamine synthase
EC 6.3.2.19 .................More Read....

EC 5. Isomerases
EC 5.1 Racemases and Epimerases
EC 5.1.1 Acting on Amino Acids and Derivatives

EC 5.1.1.1 alanine racemase
EC 5.1.1.2 methionine racemase
EC 5.1.1.3 glutamate racemase
EC 5.1.1.4 proline racemase
EC 5.1.1.5 lysine racemase
EC 5.1.1.6 threonine racemase
EC 5.1.1.7 diaminopimelate epimerase
EC 5.1.1.8 4-hydroxyproline epimerase
EC 5.1.1.9 arginine racemase
EC 5.1.1.10 amino-acid racemase
EC 5.1.1.11 phenylalanine racemase (ATP-hydrolysing)
EC 5.1.1.12 ornithine racemase
EC 5.1.1.13 aspartate racemase
EC 5.1.1.14 nocardicin-A epimerase
EC 5.1.1.15 2-aminohexano-6-lactam racemase
EC 5.1.1.16 protein-serine epimerase
EC 5.1.1.17 isopenicillin-N epimerase
EC 5.1.1.18 serine racemase

EC 5.1.2 Acting on Hydroxy Acids and Derivatives

EC 5.1.2.1 lactate racemase
EC 5.1.2.2 mandelate racemase
EC 5.1.2.3 3-hydroxybutyryl-CoA epimerase
EC 5.1.2.4 acetoin racemase
EC 5.1.2.5 tartrate epimerase
EC 5.1.2.6 isocitrate epimerase

EC 5.1.3 Acting on Carbohydrates and Derivatives

EC 5.1.3.1 ribulose-phosphate 3-epimerase
EC 5.1.3.2 UDP-glucose 4-epimerase
EC 5.1.3.3 aldose 1-epimerase
EC 5.1.3.4 L-ribulose-5-phosphate 4-epimerase
EC 5.1.3.5 UDP-arabinose 4-epimerase
EC 5.1.3.6 UDP-glucuronate 4-epimerase
EC 5.1.3.7 UDP-N-acetylglucosamine 4-epimerase
EC 5.1.3.8 N-acylglucosamine 2-epimerase
EC 5.1.3.9 N-acylglucosamine-6-phosphate 2-epimerase
EC 5.1.3.10 CDP-paratose 2-epimerase
EC 5.1.3.11 cellobiose epimerase
EC 5.1.3.12 UDP-glucuronate 5′-epimerase
EC 5.1.3.13 dTDP-4-dehydrorhamnose 3,5-epimerase
EC 5.1.3.14 UDP-N-acetylglucosamine 2-epimerase
EC 5.1.3.15 glucose-6-phosphate 1-epimerase
EC 5.1.3.16 UDP-glucosamine 4-epimerase
EC 5.1.3.17 heparosan-N-sulfate-glucuronate 5-epimerase
EC 5.1.3.18 GDP-mannose 3,5-epimerase
EC 5.1.3.19 chondroitin-glucuronate 5-epimerase
EC 5.1.3.20 ADP-glyceromanno-heptose 6-epimerase
EC 5.1.3.21 maltose epimerase
EC 5.1.3.22 L-ribulose-5-phosphate 3-epimerase
EC 5.1.3.23 UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase

EC 5.1.99 Acting on Other Compounds

EC 5.1.99.1 methylmalonyl-CoA epimerase
EC 5.1.99.2 16-hydroxysteroid epimerase
EC 5.1.99.3 allantoin racemase
EC 5.1.99.4 α-methylacyl-CoA racemase
EC 5.1.99.5 hydantoin racemase

EC 5.2 cis-trans-Isomerases

EC 5.2.1.1 maleate isomerase
EC 5.2.1.2 maleylacetoacetate isomerase
EC 5.2.1.3 retinal isomerase
EC 5.2.1.4 maleylpyruvate isomerase
EC 5.2.1.5 linoleate isomerase
EC 5.2.1.6 furylfuramide isomerase
EC 5.2.1.7 retinol isomerase
EC 5.2.1.8 peptidylprolyl isomerase
EC 5.2.1.9 farnesol 2-isomerase
EC 5.2.1.10 2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase
EC 5.2.1.11 deleted entry

EC 5.3 Intramolecular Oxidoreductases

EC 5.3.1 Interconverting Aldoses and Ketoses

EC 5.3.1.1 triose-phosphate isomerase
EC 5.3.1.2 deleted
EC 5.3.1.3 arabinose isomerase
EC 5.3.1.4 L-arabinose isomerase
EC 5.3.1.5 xylose isomerase
EC 5.3.1.6 ribose-5-phosphate isomerase
EC 5.3.1.7 mannose isomerase
EC 5.3.1.8 mannose-6-phosphate isomerase
EC 5.3.1.9 glucose-6-phosphate isomerase
EC 5.3.1.10 now EC 3.5.99.6
EC 5.3.1.11 deleted
EC 5.3.1.12 glucuronate isomerase
EC 5.3.1.13 arabinose-5-phosphate isomerase
EC 5.3.1.14 L-rhamnose isomerase
EC 5.3.1.15 D-lyxose ketol-isomerase
EC 5.3.1.16 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase
EC 5.3.1.17 4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase
EC 5.3.1.18 deleted
EC 5.3.1.19 now EC 2.6.1.16
EC 5.3.1.20 ribose isomerase
EC 5.3.1.21 corticosteroid side-chain-isomerase
EC 5.3.1.22 hydroxypyruvate isomerase
EC 5.3.1.23 5-methylthioribose-1-phosphate isomerase
EC 5.3.1.24 phosphoribosylanthranilate isomerase
EC 5.3.1.25 L-fucose isomerase
EC 5.3.1.26 galactose-6-phosphate isomerase
EC 5.3.1.27 6-phospho-3-hexuloisomerase
EC 5.3.1.28 D-sedoheptulose 7-phosphate isomerase

EC 5.3.2 Interconverting Keto- and Enol-Groups

EC 5.3.2.1 phenylpyruvate tautomerase
EC 5.3.2.2 oxaloacetate tautomerase

EC 5.3.3 Transposing C=C Bonds

EC 5.3.3.1 steroid Δ-isomerase
EC 5.3.3.2 isopentenyl-diphosphate Δ-isomerase
EC 5.3.3.3 vinylacetyl-CoA Δ-isomerase
EC 5.3.3.4 muconolactone Δ-isomerase
EC 5.3.3.5 cholestenol Δ-isomerase
EC 5.3.3.6 methylitaconate Δ-isomerase
EC 5.3.3.7 aconitate Δ-isomerase
EC 5.3.3.8 dodecenoyl-CoA Δ-isomerase
EC 5.3.3.9 prostaglandin-A1 .................More Read....

EC 4 Lyases
EC 4.1 Carbon-Carbon Lyases
EC 4.1.1 Carboxy-Lyases

EC 4.1.1.1 pyruvate decarboxylase
EC 4.1.1.2 oxalate decarboxylase
EC 4.1.1.3 oxaloacetate decarboxylase
EC 4.1.1.4 acetoacetate decarboxylase
EC 4.1.1.5 acetolactate decarboxylase
EC 4.1.1.6 aconitate decarboxylase
EC 4.1.1.7 benzoylformate decarboxylase
EC 4.1.1.8 oxalyl-CoA decarboxylase
EC 4.1.1.9 malonyl-CoA decarboxylase
EC 4.1.1.10 deleted, included in EC 4.1.1.12
EC 4.1.1.11 aspartate 1-decarboxylase
EC 4.1.1.12 aspartate 4-decarboxylase
EC 4.1.1.13 deleted
EC 4.1.1.14 valine decarboxylase
EC 4.1.1.15 glutamate decarboxylase
EC 4.1.1.16 hydroxyglutamate decarboxylase
EC 4.1.1.17 ornithine decarboxylase
EC 4.1.1.18 lysine decarboxylase
EC 4.1.1.19 arginine decarboxylase
EC 4.1.1.20 diaminopimelate decarboxylase
EC 4.1.1.21 phosphoribosylaminoimidazole carboxylase
EC 4.1.1.22 histidine decarboxylase
EC 4.1.1.23 orotidine-5′-phosphate decarboxylase
EC 4.1.1.24 aminobenzoate decarboxylase
EC 4.1.1.25 tyrosine decarboxylase
EC 4.1.1.26 deleted, included in EC 4.1.1.28
EC 4.1.1.27 deleted, included in EC 4.1.1.28
EC 4.1.1.28 aromatic-L-amino-acid decarboxylase
EC 4.1.1.29 sulfoalanine decarboxylase
EC 4.1.1.30 pantothenoylcysteine decarboxylase
EC 4.1.1.31 phosphoenolpyruvate carboxylase
EC 4.1.1.32 phosphoenolpyruvate carboxykinase (GTP)
EC 4.1.1.33 diphosphomevalonate decarboxylase
EC 4.1.1.34 dehydro-L-gulonate decarboxylase
EC 4.1.1.35 UDP-glucuronate decarboxylase
EC 4.1.1.36 phosphopantothenoylcysteine decarboxylase
EC 4.1.1.37 uroporphyrinogen decarboxylase
EC 4.1.1.38 phosphoenolpyruvate carboxykinase (diphosphate)
EC 4.1.1.39 ribulose-bisphosphate carboxylase
EC 4.1.1.40 hydroxypyruvate decarboxylase
EC 4.1.1.41 methylmalonyl-CoA decarboxylase
EC 4.1.1.42 carnitine decarboxylase
EC 4.1.1.43 phenylpyruvate decarboxylase
EC 4.1.1.44 4-carboxymuconolactone decarboxylase
EC 4.1.1.45 aminocarboxymuconate-semialdehyde decarboxylase
EC 4.1.1.46 o-pyrocatechuate decarboxylase
EC 4.1.1.47 tartronate-semialdehyde synthase
EC 4.1.1.48 indole-3-glycerol-phosphate synthase
EC 4.1.1.49 phosphoenolpyruvate carboxykinase (ATP)
EC 4.1.1.50 adenosylmethionine decarboxylase
EC 4.1.1.51 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase
EC 4.1.1.52 6-methylsalicylate decarboxylase
EC 4.1.1.53 phenylalanine decarboxylase
EC 4.1.1.54 dihydroxyfumarate decarboxylase
EC 4.1.1.55 4,5-dihydroxyphthalate decarboxylase
EC 4.1.1.56 3-oxolaurate decarboxylase
EC 4.1.1.57 methionine decarboxylase
EC 4.1.1.58 orsellinate decarboxylase
EC 4.1.1.59 gallate decarboxylase
EC 4.1.1.60 stipitatonate decarboxylase
EC 4.1.1.61 4-hydroxybenzoate decarboxylase
EC 4.1.1.62 gentisate decarboxylase
EC 4.1.1.63 protocatechuate decarboxylase
EC 4.1.1.64 2,2-dialkylglycine decarboxylase (pyruvate)
EC 4.1.1.65 phosphatidylserine decarboxylase
EC 4.1.1.66 uracil-5-carboxylate decarboxylase
EC 4.1.1.67 UDP-galacturonate decarboxylase
EC 4.1.1.68 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase
EC 4.1.1.69 3,4-dihydroxyphthalate decarboxylase
EC 4.1.1.70 glutaconyl-CoA decarboxylase
EC 4.1.1.71 2-oxoglutarate decarboxylase
EC 4.1.1.72 branched-chain-2-oxoacid decarboxylase
EC 4.1.1.73 tartrate decarboxylase
EC 4.1.1.74 indolepyruvate decarboxylase
EC 4.1.1.75 5-guanidino-2-oxopentanoate decarboxylase
EC 4.1.1.76 arylmalonate decarboxylase
EC 4.1.1.77 4-oxalocrotonate decarboxylase
EC 4.1.1.78 acetylenedicarboxylate decarboxylase
EC 4.1.1.79 sulfopyruvate decarboxylase
EC 4.1.1.80 4-hydroxyphenylpyruvate decarboxylase
EC 4.1.1.81 threonine-phosphate decarboxylase
EC 4.1.1.82 phosphonopyruvate decarboxylase
EC 4.1.1.83 4-hydroxyphenylacetate decarboxylase
EC 4.1.1.84 D-dopachrome decarboxylase
EC 4.1.1.85 3-dehydro-L-gulonate-6-phosphate decarboxylase
EC 4.1.1.86 diaminobutyrate decarboxylase
EC 4.1.1.87 malonyl-S-ACP decarboxylase
EC 4.1.1.88 biotin-independent malonate decarboxylase
EC 4.1.1.89 biotin-dependent malonate decarboxylase
EC 4.1.1.90 peptidyl-glutamate 4-carboxylase

EC 4.1.2 Aldehyde-Lyases

EC 4.1.2.1 deleted, included in EC 4.1.3.16
EC 4.1.2.2 ketotetrose-phosphate aldolase
EC 4.1.2.3 deleted
EC 4.1.2.4 deoxyribose-phosphate aldolase
EC 4.1.2.5 threonine aldolase
EC 4.1.2.6 deleted
EC 4.1.2.7 deleted, included in EC 4.1.2.13
EC 4.1.2.8 indole-3-glycerol-phosphate lyase
EC 4.1.2.9 phosphoketolase
EC 4.1.2.10 (R)-mandelonitrile lyase
EC .................More Read....